Research Technician IV

Employer
Clinical Research Management
Location
Silver Spring, MD
Posted
Oct 21, 2021
Closes
Oct 23, 2021
Ref
155550071
Industry
Science
Hours
Full Time
Perform the following general laboratory administration duties in conjunction with each technical research support area: * Assist in establishing new techniques in the laboratory based on information provided in the scientific literature supporting the technical research areas to include but not limited to Traumatology, Physiology and Immunology, Phage Biology, Microbiology, Structural Biology, Microbial Virulence, Microbial Genetics, Immunology, Molecular biology, Bioinformatics and Animal models. * Comply with occupational health and safety standards and complete all required safety, biosafety and security training classes as established by WRAIR as minimal standard in the Joint Safety Manual. * Analyze and report experimental results from each technical research support area to stakeholders and leaders. * Maintain accurate and appropriate research records including maintaining laboratory notebooks compliant with standards of laboratory work (replicability). * Maintain laboratory operation to include insuring stocks of laboratory supplies and reagents, ordering supplies and preparing supply requests for approval, annual inventory of micro-organisms, annually updating of technical research support area SOPs, maintaining a supply of clean glassware, properly disposing of hazardous biological and chemical waste, preparing reagents, and maintaining an inventory of laboratory chemicals, orderliness and cleanliness. * Integrate and coordinate scientific experiments in the field of expertise supporting each technical research area. * Work closely with other Government and Contractor personnel to plan, develop, and gain approval of human use protocols as required for the performance of tasks. * Obtain required occupational physical examinations, annual serologic tests and any required security clearance to conduct work in department laboratories. * Report any infractions of safety procedures to the facility Safety Officer within 24hrs. * Serve as Alternative Bacterial Disease Branch collateral duty officer in accordance with Safety Office and other applicable guidelines IAW WRAIR Joint Safety Manual. * Prepare, draft, research and compile data summaries and results for presentations (at least five annually or as desired) or publication (at least 5 annually or as desired) as scientific literature (IAW WRAIR policy 12-03 Authorship of Manuscripts) and for submission to the Department Chief and Public Affairs Office (PAO) or for bi-annual reports for each technical research support area. * Prepare and publish articles in peer reviewed scientific journals annually * Attend and participate in seminars, scientific conferences, and meetings to share research results in the form of scientific presentation as required. Perform the following duties relating to Bacterial Pathogenesis (Virulence and monoclonal antibodies): * Serve as a technical expert in microbial pathogenesis, microbial genetics, genomics and related virulence factors in one or more of the ESKAPEE pathogens (Enterococcus species, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Enterobacter cloacae, and Escherichia coli) (a minimum of five studies or as required) * Perform research on monoclonal antibody development for microbial pathogens of military relevance and animal testing (a minimum of five studies or as required). * Develop and recommend research protocols and experimental techniques on monoclonal antibody development for submission and approval by the department chief (a minimum of five studies or as required) and report to the COR annually. * Conduct research on projects associated with virulence factors and monoclonal antibody development for one or more of the ESKAPEE pathogens (Enterococcus species, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Enterobacter cloacae, and Escherichia coli) (a minimum of five studies or as required). * Plan, coordinate and perform microbiological studies on virulence factors and monoclonal antibody development, to include animal modeling, under biosafety level two (a minimum of five studies or as required). * Express and purify recombinant proteins for antibody production, deliver antibodies, crystallize antigen: antibody complexes and mass spectrometry of all products.#06022021

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