Research Associate II (Multiplex)

Employer
Frederick National Laboratory
Location
Frederick, MD
Posted
Dec 01, 2020
Closes
Dec 06, 2020
Ref
1471083909
Function
Analyst, Research
Industry
Science
Hours
Full Time
Research Associate II (Multiplex) Job ID: req1553 Employee Type: exempt full-time Facility: Frederick: Ft Detrick Location: PO Box B, Frederick, MD 21702 USA The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc. The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases. Our core values of accountability, compassion, collaboration, dedication, integrity, and versatility serve as a guidepost for how we do our work every day in serving the public's interest. Position Overview: PROGRAM DESCRIPTION The Clinical Services Program's mission is to perform sequential studies using samples obtained from patients with cancer, AIDS, chronic granulomatous disease or other diseases associated with immunologic dysfunction. The Clinical Support Laboratory (CSL) provides dedicated support to clinical investigators in the Center for Cancer Research (CCR) of NCI. Services include specimen processing and testing in support of clinical trials as well as testing in support of investigator initiated basic research. The laboratory also provides dedicated support to specific programs/projects sponsored by the Division of Cancer Epidemiology and Genetics, NCI and the Division of Clinical Research, NIAID. The CSL also provides shared service support that is available to other NIH investigators. KEY ROLES/RESPONSIBILITIES Primary responsibilities include: * Testing of human blood samples obtained from cancer patients enrolled in NIH-sponsored clinical trials * Using serum, plasma, & other matrices, the successful candidate will be responsible for performing multiplex immunoassays using state of the art platforms of MesoScale (MSD) and Luminex platforms * The candidate will work in a timeline-driven environment that requires the ability to work simultaneously on multiple and diverse projects involving protein biomarkers in clinical research, patient testing (CLIA); and manufacturing material (GxP). Additional responsibilities may include developing ELISA and immunogenicity assays for ADA, PK * Desired background in performing immunoassays; accurate entry of sample information into the laboratory sample accession system and other databases * Candidate will maintain inventory of sample aliquots withdrawn. Accurate data recording. Ordering and restocking of laboratory areas as assigned, routine cleaning of laboratory work areas and equipment, and maintaining related documentation * Secondary responsibilities: * may involve sample processing, cell culture, or nucleotide extraction * Work involves exposure to potentially infectious human, and non-human primate blood and blood products. Besides potential for exposure to hazardous biological agents, exposure to potentially hazardous chemicals is a possibility. Laboratory work requires the use of personal protective equipment and adherence to strict safety protocols and will be conducted in BSL-2 laboratory areas. Work involves rapid mental/muscular coordination, good vision and ability to multitask. May also involve standing, walking, climbing, working alone or closely with others. Requires attention to detail, and the ability to work accurately and follow established Standard Operating Procedures with a reproducible outcome. Knowledge of general laboratory skills and ability to organize workflow. Must be able to demonstrate proficiency with computers and accurately enter information into database programs. Ability to lift and carry up to 25lbs. BASIC QUALIFICATIONS * Possession of Bachelor's degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA). Foreign degrees must be evaluated for US equivalency * In addition to educational requirements, a minimum of five (5) years of job-related biomedical experience * Ability to obtain and maintain a security clearance PREFERRED QUALIFICATIONS * Working knowledge of systems utilized and program principles such as: Basic subject matter of specialty area (ie, biochemistry, immunology, cell biology, etc.); advanced data reporting techniques; and basic laboratory techniques germane to the specialty area (ie Lab bench experiments, safety procedures, instrument operation, etc.) * Experience with multiplex immunoassays Luminex and/or MSD as well as a demonstrated ability to trouble shoot assays. JOB HAZARDS * This position is subject to working with or have potential for exposure to animal(s) and/or animal material(s) * This position is subject to working with or have potential for exposure to infectious material, requiring medical clearance and immunizations * This position is subject to working with radioactive material and requires to become an approved radiation worker Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW) #readytowork

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