Research Associate II (WRAIR Entomology Branch)

Location
Silver Spring, MD
Posted
Jun 14, 2017
Closes
Jul 06, 2017
Function
Analyst, Research
Industry
Research
Hours
Full Time
GDIT is seeking a Research Associate II to support WRAIR's Entomology Branch by performing the following tasks:

 

        Develop and maintain the department’s ability to produce infectious pathogens such as (but not limited to) human and rodent malaria, leishmania, dengue virus, and Zika virus. All tasks apply to production of any such pathogen, most of which are propagated concurrently within the lab.
          Continually maintain parasite life cycle in animal models and mosquitoes or sandflies, to include multiple parasite species and strains maintained concurrently, resulting in hundreds of plates, flasks, and infected animals needing attention each day, depending on demand. Maintaining these cultures might require working weekends based on the number of cultures in process and external requests. The contractor will endeavor to improve efficiency, capability or capacity of new and existing culture methods and will keep abreast of current and emerging literature concerning parasite/viral propagation and culture.Prepare vectors for infectious feeds and infect vectors using appropriate feeding devices, direct animal feeds, or injection methods. Feedings/injections will occur multiple times a week, sometimes several times a day, and sometimes on weekends, depending on demand. The contractor shall communicate with supervisors and other personnel to determine demand and adjust production and schedule accordingly.
        Cultivate and continually maintain parasites, viruses, etc. in tissue culture and maintain laboratory records of parasite/virus growth and differentiation. Monitor parasite/virus development in infected vectors and in vivo animal infections by dissection and microscopic examination or molecular techniques, as appropriate, and maintain laboratory records of parasite/viral development and propagation. Provide a final project record and report which shall include written reports, data summaries, troubleshootedand maintained databases, published research findings in peer-reviewed journals, and presented research findings at scientific meetings and conferences.Be familiar with all cell culture, microbiological, molecular and other applicable techniques and methodology, Biological Safety Level 2 safety procedures, use of laboratory personal protective equipment, be familiar with WRAIR safety standard operating procedures (SOP), and attend WRAIR annual safety courses and other training, as offered.Independently plan, execute and analyze basic research studies on the in vitro and in vivo cultivation of all parasite stages, viral propagation, vector-pathogen interactions, transmission biology and other applicable avenues of scientific investigation.Assist in the preparation of infected vectors and execution of challenges for CHMI clinical trials according to protocol, schedule, and applicable regulatory governance.Assist with the preparation and stewardship of laboratory reagents, methodology, equipment, biological materials and other materials pertaining to experiment execution and laboratory cleanliness and safety. Work collaboratively to achieve the above. May require working evenings and weekends
Education Bachelors Degree in a biological science.

Qualifications 2-5 years of related experience in mammalian tissue culture and malaria parasite culture techniques.

 Experience with insect rearing and BSL-2 containment preferred.  As a trusted systems integrator for more than 50 years, General Dynamics Information Technology provides information technology (IT), systems engineering, professional services and simulation and training to customers in the defense, federal civilian government, health, homeland security, intelligence, state and local government and commercial sectors.With approximately 32,000 professionals worldwide, the company delivers IT enterprise solutions, manages large-scale, mission-critical IT programs and provides mission support services.GDIT is an Equal Opportunity/Affirmative Action Employer - Minorities/Females/Protected Veterans/Individuals with Disabilities.