Senior Biologist for Drug Discovery (WRAIR- In vitro Core)

Silver Spring, MD
May 02, 2017
Aug 17, 2017
Full Time
GDIT is seeking a Senior Biologist for Drug Discovery (In Vitro Core) to support the mission of the Experimental Therapeutics (ET) Branch of the Walter Reed Army Institute of Research (WRAIR).  The mission of the WRAIR Branch of Experimental Therapeutics is to discover and develop new pharmaceutical agents to protect military members from death, disease, and injury. The ET Branch is organized into three distinct departments which contribute to the different phases leading to FDA drug approval. The three comprising departments are the Departments of Drug Discovery, Drug Development, and Clinical Pharmacology.

This position is in direct support of the Department of Drug Discovery. Specific tasks include:

  • Manage and implement the evaluation of drugs in vitro.
  • Function as the ET biological lead for the Combating Antibiotic Resistant Bacteria (CARB) program, performing in vitro laboratory management and experimental design and execution.
  • Generate experimental protocols, study reports for FDA submissions, contribute to IACUC animal protocols, and formulate proposals for research funding that address Branch goals for antimicrobial (bacteria, malaria, leishmania, and other parasites as required) for drug discovery and development.
  • Develop and oversee the execution of bacterial screening and target-based enzymatic assays for antimicrobial drug discovery and development.
  • Initiate and maintain bacteria and parasite cultures for use in in vitro assays and animal studies.
  • Design and oversee execution of molecular protocols for bacteria and parasite speciation and resistance analysis.
  • Be responsible for tracking and assisting with project accounting and planning for project future requirements including requesting and preparing supply and equipment purchase documents for approval by the COR and ET leadership.
  • Manage program/projects related to the tasks in the PWS.
  • Attend and present at relevant national scientific conferences, if required by Department of Discovery.

Knowledge base: Have working knowledge of antimicrobial drug discovery and development and have the ability to design and execute experimental protocols. Ability to generate peer-reviewed publications, study reports for FDA submission, funding proposals, and IACUC animal protocols, as required. Ability to carry out molecular protocols for malaria speciation and resistance analysis. Shall assist and manage all aspects of the CARB program as described in the Presidential Initiative. Shall track and account for supply and equipment requirements of the Department of Drug Discovery.

Physical Capabilities: Work may involve long periods of standing and handling of BSL2 level infectious agents, toxic chemicals, and blood-borne pathogens. Work will require the ability to operate research equipment requiring manual dexterity. The ability to handle research animals is also needed.

Work environment: Biosafety Level (BSL) 2 laboratory and animal BSL 2 laboratory. Potential exposure to infectious agents, toxic chemicals, and blood-borne pathogens. Must be able to wear appropriate personal protective equipment. Will also work in an office setting.

Education Ph.D. in Molecular Biology, Microbiology, or related field.

Qualifications 10-15 years of related experience in scientific research, analysis and/or engineering.

  As a trusted systems integrator for more than 50 years, General Dynamics Information Technology provides information technology (IT), systems engineering, professional services and simulation and training to customers in the defense, federal civilian government, health, homeland security, intelligence, state and local government and commercial sectors.With approximately 32,000 professionals worldwide, the company delivers IT enterprise solutions, manages large-scale, mission-critical IT programs and provides mission support services.GDIT is an Equal Opportunity/Affirmative Action Employer - Minorities/Females/Protected Veterans/Individuals with Disabilities.