Malaria Liver Stage Screening Support Technician (WRAIR-In Vitro Core)

Silver Spring, MD
May 02, 2017
Aug 17, 2017
Specialty Trades
Full Time
GDIT is seeking a Malaria Liver Stage Screening Support Technician (In Vitro Core) to support the mission of the Experimental Therapeutics (ET) Branch of the Walter Reed Army Institute of Research (WRAIR).  The mission of the WRAIR Branch of Experimental Therapeutics is to discover and develop new pharmaceutical agents to protect military members from death, disease, and injury. The ET Branch is organized into three distinct departments which contribute to the different phases leading to FDA drug approval. The three comprising departments are the Departments of Drug Discovery, Drug Development, and Clinical Pharmacology.

This position is in direct support of the Department of Drug Discovery. Specific tasks include:

    Provide in vitro liver stage malaria and toxicity screen support.Perform in vitro Inhibition of Liver Stage Development Assay (ILSDA).Manage the isolation of malaria sporozoites from mosquito salivary glands.Assist in optimizing an in vitro screen for assessing drug effects on liver stage of malaria.Execute in vitro assay for cell toxicity (in HepH2 and macrophages Raw264.7 cells).Provide malaria sporozoites to support the in vivo mouse malaria model systems.Analyze and summarize experimental data for reports and presentations and publications.Maintain a safe working environment and adhere to applicable safety regulations.Attend and present at relevant national scientific conferences, if required by Department of Discovery.

Physical Capabilities: Physical Capabilities: Work may involve long periods of standing and handling of BSL2 level infectious agents, toxic chemicals, and blood-borne pathogens. Work will require the ability to operate research equipment requiring manual dexterity.

Work environment: Biosafety Level (BSL) 2 laboratory and animal BSL 2 laboratory. Potential exposure to infectious agents, toxic chemicals, and blood-borne pathogens. Must be able to wear appropriate personal protective equipment. Will also work in an office setting.

Education MS in Microbiology, biomedical field or related field.

Qualifications 5-8 years of related experience in scientific research, analysis and/or engineering.

  As a trusted systems integrator for more than 50 years, General Dynamics Information Technology provides information technology (IT), systems engineering, professional services and simulation and training to customers in the defense, federal civilian government, health, homeland security, intelligence, state and local government and commercial sectors.With approximately 32,000 professionals worldwide, the company delivers IT enterprise solutions, manages large-scale, mission-critical IT programs and provides mission support services.GDIT is an Equal Opportunity/Affirmative Action Employer - Minorities/Females/Protected Veterans/Individuals with Disabilities.