Will independently serve as a lab manager to satisfy the overall operational objectives of the Developmental Therapeutics and Pharmacology Unit in the National Institute of Neurological Disorders and Stroke. The primary objective is to provide services and deliverables through performance of support services.Minimum EducationMaster'sResume Max Pages15Certifications & LicensesNeuroscience, Computer Science, Engineering, or related fieldsSkills (Ranked By Priority)1. Ability to evaluate own results and those of others, including those in published literature.2. Background in molecular techniques, demonstrate ability to perform experiments independently and with minimal supervison.3. Proficiency in the operation of computer and general data acquisition programs.4. Excellent analytical, organizational, interpersonal, and time management skills5. Strong communication skills, both oral and written6. Ability to rapidly acquire knowledge in new fields and to understand and if necessary adapt published procedures to own needs.1, 2, 3, 4, 5 _represents priority rankings, where 1 is highest priority and 5 is lowest priority of those ranked_SoftwareAdobe PhotoshopAdobe ProGraph Pad PrismMicrosoftField of StudyNeuroscienceDELIVERABLESClean Equipment - DailyRun Validation - DailyInspect Equipment - DailyMeet with lab members to present updates - WeeklyMaintain work documents and products - DailySTATEMENT OF WORK DETAILSfunctional responsibilitySupports the planning and execution of research experiments in the context of the laboratory's overall research program.descriptionAdvance the science in the laboratory through new procedures and discoveries.1descriptionMaintain and culture human and rodent cancer cell lines for in vitro experimentsdescriptionPrepare human and rodent tumor cells for in vivo tumor implantations.descriptionAssist when needed with animal workdescriptionPerform work on human specimens in support of ongoing clinical trialsdescriptionMaintain and culture human and rodent cancer cell lines for in vitro experiments.descriptionPrepare human and rodent tumor cells for in vivo tumor implantations.descriptionAssist when needed with animal work, including monitoring and treatment of tumor-bearing mice, handling mice for injection of tumor cells and drug treatments, intraperitoneal drug injections and oral gavage, tail vein injections, subcutaneous saline injections, measurement of tumors, weight checks, tumor harvest and assessment of health status.descriptionPerform work on human specimens in support of ongoing clinical trials, including vessel/endothelial cell isolation, single cell disassociation of tumor tissue, rtPCR, PCR, western blots, immunohistochemistry, immune fluorescence, RNA-in situ hybridization, and others.descriptionMaintain records of all experiments in laboratory notebook, including planning, execution, outcome and evaluation of experiments performed.descriptionOrder equipment and supplies in the NINDS ordering system, POTSdescriptionAssist with development of orders for large laboratory equipment.descriptionMaintain and catalog recombinant DNA stocks, plasmids and vectors, flow cytometry antibody stocks and tissue bio-specimens.descriptionMaintain stocks of available cancer cell lines in liquid nitrogen and update virtual inventory.descriptionWork with staff to perform histology and histological labeling techniques including immunostaining Operate and troubleshoot laboratory equipment.descriptionAnalyze data and prepare presentations and present for NIH, regional and national meetings.descriptionWork with staff on general laboratory maintenance, including clean water baths, prepare and keep tissue culture media stocked, check incubator temperature and CO2 levels; maintain tissue culture equipment and supplies Maintain patient confidentialityfunctional responsibilitySupports laboratory staff on research projects and techniques.descriptionWork with staff on the interpretation of experiments performed by research scientists.descriptionIndependently direct and conduct special research projects that have a high priority for the laboratory with special emphasis in the development of Client research treatments.descriptionReview scientific data to determine if a research program can be developed around an idea or data package.functional responsibilityMaintains laboratory equipment and the training of others in their use.descriptionTrain staff on the proper usage of laboratory instruments and equipment.2descriptionCalibrate, maintain and troubleshoot instruments and equipment in the laboratory.descriptionOperate, troubleshoot and train others to use laboratory equipment and software.3descriptionProvide advice and assistance to users in designing experiments, using instrumentation, data acquisition and analysis, and preparing figures for publication.functional responsibilityAssists in maintaining adequate space and facilities for ongoing and projected research studies.descriptionParticipate in the laboratory's review of future proposals for resource allocations.functional responsibilityEvaluates, analyzes and interprets research data, communicates results and methods in reports, presentations, and manuscripts.descriptionWrite technical reports and prepare manuscripts.descriptionConduct bioinformatics data analyses and statistical analyses; prepare data for abstracts and manuscripts.descriptionMaintain a detailed and up-to-date electronic laboratory notebook detailing all experiments.descriptionResponsible for data management for all processed compoundsdescriptionMust ensure project data quality; analyze and interpret project datadescriptionProvides interpretation of results, guidance, and scientific support to the management team.descriptionProvide scientific and technical expertise to all visiting fellows, post-docs, and technicians.5descriptionPrepare data for authorship of manuscripts.functional responsibilityCoordinates with junior staff to modify research protocols.descriptionCoordinate with IT staff on all software issues specific to the chemistry group and on all computer problems.descriptionIdentify and advise IC leadership on opportunities and program areas, research gaps and relevant program needs; make recommendations for consideration.descriptionMentors junior level scientists4descriptionAttend laboratory meetings and present findings to staff.1, 2, 3, 4, 5 _represents priority rankings, where 1 is highest priority and 5 is lowest priority of those ranked_