Molecular Biologist

Astrix Technology Group
Bethesda, MD
Jul 31, 2022
Aug 08, 2022
Accountant, IT
Full Time
*ORGANIZATIONAL HIERARCHY* National Institutes of Health (NIH) National Cancer Institute (NCI) Center for Cancer Research (CCR) Laboratory of Pathology (LP) NCI-COMPASS Section *ROLES / RESPONSIBILITES* . Extract DNA/RNA from patient materials (primarily unstained slides, FFPE blocks, peripheral blood, bone marrow, plasma and other biological fluids). . Use both manual and automated technologies existing in the laboratory. . Independently develop and improve existing technologies required for the Molecular Diagnostics Section program under a direction of lab technical director; develop and revise SOPs for extraction of DNA from bodily fluids such as cerebrospinal fluid or improve an existing custom next generation sequencing (NGS) assay and other procedures. . Macrodissect tissues of interest from unstained slides using manual or automated technologies. . Independently perform newly laboratory developed DNA and RNA Next-generation sequencing assays. The assay procedure is highly complex and involve over 100 steps for library preparation. The final libraries are sequenced on a high throughput sequencer, Illumina NextSeq 550 or NovaSeq 600. The results are used for pathology diagnosis, therapy, and clinical research. . Account for and accession submitted materials into the Laboratory's existing databases, including SoftPath and COMPASS LIMS. . Track orders and material workflow in existing databases, including CRIS, SoftPath and COMPASS LIMS. . Ensure compliance with CAP and CLIA laboratory regulations. . Adhere to policies set forth for the protection of human subjects' research and patient care privacy laws; abide by the Health Insurance Portability and Accountability Act (HIPPA) and the Federal Privacy Act. . Ensure adherence to standard operating procedures (SOPs) in accordance with regulatory requirements mandated by LP's accrediting bodies. . Organize the lab daily operation tasks. Perform QC/QM for weekly clinical tests, monthly NGS QC review, and CAP self-inspection. *BASIC REQUIREMENTS* . Bachelor's or Master's degree in Biology, Molecular Biology or a related discipline. . Minimum of two (2) years of experience in a molecular diagnostics laboratory or molecular biology research laboratory. . Experience with PCR, NGS, DNA/RNA extraction from tissues, blood, etc. . Extensive experience with adherence to the technical, quality and safety standards set forth by the College of American Pathologists relating to Molecular Diagnostic procedures. . Experience with Microsoft Office Suite (MS Word, Excel, Outlook) and laboratory information management system. . Strong communications skills, both oral and written. . Excellent analytical, interpersonal, organizational and time management skills. *LOCATION* The world-famous Building 10 on NIH's main campus in Bethesda Maryland IND123 Job Type: Full-time Pay: $65,000.00 - $75,000.00 per year Schedule: * 8 hour shift Work Location: One location