EXPERT SCIENTIST

SCIENTIST Corixa Corporation d/b/a GlaxoSmithKline Vaccines seeks Expert Scientist in Rockville, MD to perform aseptic cell culture development activities for recombinant protein vaccine antigens that will be directly used for clinical & commercial vaccine candidate manufacturing processes. Req: Master's (or for. equiv.) in Biology, Cellular & Microbial Biology or related + 4 yrs exp. in (1) mammalian platform based pre-GMP cell line development activities & co-authoring Drug substance CMC section for regulatory filings (cell line derivation report & raw material risk assessment); 2) cell culture & viral vector production processes related instrumentation, incl. automated bench-top bioreactor (AMBR15/250 & 3L Bioreactor) as well as PAT technologies (Vicell, Cedex Bio HT analyzer, Nova Bioprofile 400, or Metaflex); 3) CMC early-stage upstream process development workflow; 4) planning, executing & performing data analysis using Design of Experiments (DoE) & Multivariate analysis (MVA); & 5) implementing advanced high throughput bioanalytical assays for early product characterization of vaccine candidates. Employer will also accept a Bachelor's (or for. equiv.) in Biology, Cellular & Microbial Biology, or related + 6 yrs of post-baccalaureate, progressively responsible experience in the above. Resumes to faith.m.donaher@gsk.com job code: JG